Sophie Nguyen
| Email: sophie.tnguyen.01 | Phone: (940) 273-0910 |
| Location: Houston, TX | LinkedIn: sophie-nguyen-19423986 |
Professional Summary
Bioinformatics professional with hands-on experience in software development, data warehousing and solutions, and cloud-based workflow. I’ve worked across diverse tech stacks to support data-driven research and application development.
Skills
- Languages: Python, SQL, Spark, BigQuery, Javascript, Java
- Tools: Git, Docker, AWS, Terraform, DBT, Airflow , Tableau —
Experience
Cloud Engineer
Baylor College of Medicine, Human Genome Sequencing Center | Sep 2025 - Current
Senior Scientific Programmer
Baylor College of Medicine, Human Genome Sequencing Center | April 2023 - June 2025
- Fine-tuned a deep learning variant calling model by augmenting training data from public genomic datasets, achieving a 40% improvement in detecting low-frequency variants.
- Analyzed AWS Cost & Usage Reports to monitor spending, ensure budget compliance, and identify cost anomalies, resulting in $2,000 monthly cloud savings and improved resource allocation efficiency.
- Engineered Dockerized applications and integrated them into serverless workflows, optimizing scalable genomic infrastructure for high-throughput data ingestion, quality control, and variant reporting.
- Used AWS Inspector to assess container security and unintended network exposure, reducing high-risk vulnerabilities by over 90% per monthly cycle and strengthening application security and compliance.
- Benchmarked bioinformatics tools and validated clinical genomic assays to ensure SOP compliance and CAP/CLIA standards. Documented findings and communicated key insights to stakeholders.
- Supported research initiatives through bioinformatics analysis by leveraging statistical methods to extract key insights and deliver actionable reports that informed critical research decisions.
Associate Data Scientist
Immatics Biotechnologies | Jan 2020 - Mar 2023
- Designed and implemented a graphical user interface with an optimized SQL database, enabling efficient data exploration, insightful visualization, and advanced data mining for complex research initiatives.
- Utilized web design principles to develop and integrate new features into in-house web interfaces, supporting growing user demand for internal databases and laboratory information management systems.
- Conducted comprehensive testing of front-end and back-end systems, ensuring robust data integrity, performance, and user experience across all functionalities.
- Integrated proteomics tools with multiple modalities into internal mass spectrometry pipelines, driving the discovery of novel immunotherapeutic HLA peptides.
- Managed reliable execution of bioinformatics pipelines by coordinating scheduling and minimizing downtime through prompt diagnosis and efficient resolution of technical issues during runtime.
Graduate Research Assistant
Georgia Institute of Technology | Aug 2018 - Dec 2019
- Successfully performed exploratory single-cell RNA sequencing analysis on blood samples to investigate gene expression of immune cells, extracting key biological insights, and communicating these effectively.
- Automated scripts to process and analyze large-scale proteomic datasets for mass-spec facilities.
Data Science Intern
Corteva Agriscience | May 2019 - Aug 2019
- Leveraged high-performance computing and web scraping for genomic mining of bioactive natural products, building expression profiles with comparative transcriptomic tools.
- Applied supervised learning to identify biosynthetic gene clusters and their potential functionalities.
Education
Master of Science in Bioinformatics
Georgia Institute of Technology | 2018-2019
- Relevant coursework: Data&Visual Analystics; Computational Genomics; Programming for Bioinformatics; Introduction to Database System; Human Genetics; Genomics&APplied Bioinformatic.
Bachelor of Arts in Biochemistry
College of Wooster | 2012-2016
- Relevant coursework: Probability&Statistics; Genes&Genomes;Transition to Advanced Matehmatics
Certifications
AWS Certified Solutions Architect – Associate
- Issued Jan 2024 · Expires Jan 2027
AWS Certified Cloud Practitioner
- Issued Sep 2023 · Expires Sep 2026